The plot revolves around Jonathan Reid, a doctor who has turned into a vampire. Coming to terms with his undead condition, he must deal with being torn between the Hippocratic Oath and his newfound bloodthirsty nature. The player is under no obligation to kill to finish the game. Dialogue options can be used for hunting prey to feed on, which replenishes strength and levels up the lead character. Weapons and supernatural abilities are employed while combating enemies. London serves as a fictionalized open world composed of four districts, which can all be destroyed based on the player's actions.